The Institute collects, registers, files and digitalizes evidence and documents from across Greece, the Balkans and Europe, concerning the history and the social movements of tobacco.

It records the social, ethnic and gender layers and structures of the "tobacco professions", the trade unions and guilds and the overwhelming impact of the tobacco trade in the financial and social transformations that took place in national and local level.

Furthermore, the ISMTH applies for and works on regional, international, European and interstate programs of cultural and historical content within the framework of regional development.